Transport and Bioavailability Studies of Astragaloside IV, an Active Ingredient in Radix Astragali
نویسندگان
چکیده
منابع مشابه
Anti-hepatitis B virus activities of astragaloside IV isolated from radix Astragali.
Total ethanol extract and saponins from Chinese herb radix Astragali (huangqi) have been previously shown to possess anti-hepatitis B virus (HBV) activities in vitro. To identify the active ingredients, we isolated a triterpenoid saponin that was determined to be astragaloside IV. In the human HBV-transfected liver cell line HepG(2) 2.2.15, astragaloside IV effectively suppressed secretion of H...
متن کاملDetermination of astragaloside IV in Radix astragali (Astragalus membranaceus var. monghulicus) using high-performance liquid chromatography with evaporative light-scattering detection.
A reverse-phase high-performance liquid chromatographic method is developed for the determination of astragaloside IV, a characteristic constituent in Radix Astragali. Samples are analyzed by means of a reverse-phase column (Zorbax Eclipse XDB C18) using acetonitrile and water under gradient conditions as the mobile phase for 30 min. An evaporative light-scattering detector is used and set at a...
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15 صفحه اولComparison of the Immunoregulatory Function of Different Constituents in Radix Astragali and Radix Hedysari
Radix Astragali (RA), known as "Huangqi" in China, is one of the most popular herbal medicines known worldwide to reinforce "Qi". RA is traditionally prepared from the dried roots of Astragalus membranaceus (MJHQ) and A. membranaceus var. mongholicus (MGHQ). Radix Hedysari is named "Hongqi" (HQ), which is similar to RA. We assessed and compared the chemical constituents and bioactivity of RA an...
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ژورنال
عنوان ژورنال: Basic <html_ent glyph="@amp;" ascii="&"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&"/> Toxicology
سال: 2004
ISSN: 1742-7835,1742-7843
DOI: 10.1111/j.1742-7843.2004.t01-1-pto950508.x